CCO Oncology Podcast

Clinical Highlights: Oral SERDs for Patients With HR+/HER2- ESR1-Mutated Advanced Breast Cancer

Episode Summary

Audio podcast with key highlights on current and emerging data for the use of oral SERDS in patients with HR+/HER2- ESR1-mutated advanced breast cancer. Listen to experts put new trial results into context and cover practical perspectives and takeaway points for your everyday practice.

Episode Notes

In this episode, listen to Virginia Kaklamani, MD, DSc; Erica L. Mayer, MD, MPH; and Laura M. Spring, MD, share their clinical insights and takeaways from a live symposium, including from key abstracts presented at the 2024 San Antonio Breast Cancer Symposium:

• Estrogen receptor mutations in patients With HR-positive/HER2-negative advanced breast cancer
• Current guideline recommendations for when to pursue ESR1 mutation testing mutations in patients with HR-positive/HER2-negative advanced breast cancer
• Choice and sequencing of next line of systemic therapy for ESR1-mutated advanced breast cancer based on tumor molecular alterations
• Overview of class-related and unique adverse events with approved and emerging oral SERDS
• Expert recommendations for the management of oral SERDs-related adverse events

Program faculty:

Virginia Kaklamani, MD, DSc
Professor of Medicine
Ruth McLean Bowman Bowers Chair in Breast Cancer Research and Treatment
A.B. Alexander Distinguished Chair in Oncology 
Leader
Breast Oncology Program
UT Health San Antonio
MD Anderson Cancer Center
San Antonio, Texas

Erica L. Mayer, MD, MPH
Director of Breast Cancer Clinical Research
Dana-Farber Cancer Institute
Associate Professor in Medicine
Harvard Medical School
Boston, Massachusetts

Laura M. Spring, MD
Breast Medical Oncologist
Mass General Hospital Cancer Center
Harvard Medical School
Boston, Massachusetts 

Resources:
To download the slides associated with this podcast discussion, please visit the program page.