| In this podcast episode, 3 experts answers questions on the management of hemophilia A from a live webinar. Topics include:  Which patients should have pharmacokinetic-guided therapy?Toxicities with PEGylated extended half-life productsFactor VIII and bone healthFactor VIII peaks, thrombotic risk, and cardiovascular diseaseChoosing between extended half-life products and emicizumab for active patientsRole of fitusiran in the treatment paradigm if approved
 Presenters:Miguel A. Escobar, MD
 Professor of Medicine and Pediatrics
 Department of Hematology
 University of Texas Health Science Center
 McGovern Medical School
 Director
 Gulf States Hemophilia and Thrombophilia Center
 Houston, Texas
 Mark Reding, MDProfessor of Medicine
 Division of Hematology, Oncology, and Transplantation
 Director
 Center for Bleeding and Clotting Disorders
 University of Minnesota
 Minneapolis, Minnesota
 Guy A. Young, MDProfessor of Pediatrics
 Director, Hemostasis and
 Thrombosis Center
 Children’s Hospital Los Angeles
 University of Southern California
 Keck School of Medicine
 Los Angeles, California
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