CCO Oncology Podcast

Evolving Role of BTK Inhibitors in CLL: Experts Answer Your Questions

Episode Summary

In this podcast episode, listen to Farrukh T. Awan, MD, and Nicole Lamanna, MD, answer questions from an audience of healthcare professionals on the evolving role of BTK inhibitors in CLL, including sequencing, combinations, and novel agents.

Episode Notes

In this episode, Farrukh T. Awan, MD, and Nicole Lamanna, MD, answer questions from an audience of healthcare professionals on topics related to the use of BTK inhibitors for the management of chronic lymphocytic leukemia (CLL). The topics covered include:

• Whether it is justifiable to use chlorambucil plus obinutuzumab as a control arm in a registrational trial today
• Relevance of overall response rate vs progression-free survival for BTK inhibitor therapy
• Approval of ibrutinib/venetoclax combination therapy for patients with CLL
• Key differences between zanubrutinib and acalabrutinib in the treatment of patients with CLL
• How to transition/overlap next therapy in patients with CLL with progression while receiving a BTK inhibitor

Faculty:
Farrukh T. Awan, MD
Associate Professor of Internal Medicine
Director of Lymphoid Malignancies Program
Harold C. Simmons Comprehensive Cancer Center
University of Texas Southwestern Medical Center
Dallas, Texas

Nicole Lamanna, MD
Associate Professor
Leukemia Service
Director of CLL Program
Hematologic Malignancies Section
Department of Medicine
New York-Presbyterian/Columbia University Medical Center
New York, New York

Link to the complete program, including downloadable slidesets and an on-demand webcast:
https://bit.ly/3EjvSKm